how much do you weigh Turks? What pace are you running, what shoes are you using ? The fact that it's continual calf strains must mean that either your heel is going down too far on strike (which could mean that your shoes are too flat or too supple for your weight or just f*cked from overuse in general) or that your going up on your toes too much on pushoff. For the ankle swelling that would need medical investigation if it continues because it could be circulatory or even excessive Urea build up.
Some people's feet and ankles swell up just from sitting down for too long at a time due to poor circulation but running shouldn't cause that, you could always try compression socks though if it occurs again, see if that makes a difference, especially with winter coming on, I use them from October to March but then it's always brass monkeys around here in that period.